Hao Zhen

Implantable BCI Systems & Translational Neuroengineering

My work spans the architecture and translation of high-bandwidth implantable brain–computer interfaces—from neural acquisition and wireless telemetry to system reliability, preclinical validation, clinical deployment, and neural information processing.

  • Implantable BCI Systems
  • Translational Neuroengineering
  • Neural Information & Decoding

Research

Implantable BCI Systems

My work examines the architecture of high-bandwidth implantable neural interfaces and the engineering constraints that determine their real-world performance.

  • neural recording systems
  • implant electronics
  • wireless telemetry
  • bandwidth
  • power and thermal constraints
  • latency
  • synchronization
  • distributed and multi-region BCI systems

How can implantable neural interfaces acquire and transmit increasingly large amounts of neural information while remaining low-power, reliable, and clinically practical?

Translational Neuroengineering

This work extends from experimental neurotechnology to systems designed for reliable operation in preclinical and clinical environments.

  • verification and validation
  • system reliability
  • chronic operation
  • preclinical testing
  • regulatory engineering
  • clinical deployment
  • first-in-human translation

How do we translate experimental neural interfaces into reliable systems that can operate in real preclinical and clinical environments?

Neural Information & Decoding

My research examines how neural information should be represented, preserved, transmitted, and modeled across future brain–computer interfaces.

  • raw neural signals
  • spikes and LFP
  • neural representations
  • neural information throughput
  • multimodal neural data
  • neural decoding
  • AI-native BCI architectures

What neural information should future BCIs preserve, transmit, and model?

Research Directions

  • High-Bandwidth Implantable BCI Systems

    System-level constraints across neural acquisition, onboard processing, wireless telemetry, power, latency, and decoding.

  • Neural Information Representation

    Understanding the tradeoff between raw neural signals, spikes, LFPs, information preservation, bandwidth, and decoding performance.

  • Chronic Neural Interface Stability

    Developing system-level metrics for evaluating long-term intracortical interface stability.

Selected Work

Paradromics

Implantable Brain–Computer Interfaces

System-level engineering and translation of implantable BCI systems spanning neural communication platforms, verification and validation, preclinical studies, regulatory testing, and early clinical deployment.

Applied Materials

Complex High-Reliability Systems

Engineering of complex semiconductor manufacturing systems, with a focus on high-reliability electrical hardware and system integration.

Professional Service

Massachusetts General Hospital

Institutional Review Board Member

About

Hao Zhen works at the intersection of implantable neurotechnology, systems engineering, and clinical translation. His experience spans BCI system architecture, neural communication hardware, verification and validation, preclinical studies, regulatory engineering, and early clinical deployment, building on earlier work in complex semiconductor manufacturing systems.

His research focuses on high-bandwidth implantable neural interfaces, neural information transmission, chronic interface reliability, distributed BCI systems, and neural decoding. He holds an M.Eng. in Engineering Management from Cornell University and a B.S. in Electrical and Computer Engineering from Northeastern University.

Contact

For research and professional inquiries, connect through ORCID or GitHub.